Are Helicobacter pylori and other Helicobacter species infection associated with human biliary lithiasis? A meta-analysis.

ABSTRACT:

Background

Since the isolation of Helicobacter species in biliary system, a hypothetical question was raised about the role of these agents in the development of cholelithiasis. This meta-analysis is to explore the association between the Helicobacter infection and biliary lithiasis.

Methodology/principal findings

A systematic literature search was performed to identify all eligible articles. Meta-analysis which was carried out using odds ratio and random effect model, 95% confidence intervals for odds ratio was calculated. Quantitative assessment of heterogeneity was explored by chi-square test with significance set at P value 0.10 and was measured using I(2) statistic. Eighteen studies published between 1998 and 2011 were finally eligible for meta-analysis. H. pylori, H. b

SUBMITTER: Zhou D 

PROVIDER: S-EPMC3210793 | biostudies-literature | 2011

REPOSITORIES: biostudies-literature