Multicomponent catalytic asymmetric aziridination of aldehydes.

ABSTRACT: The first multicomponent catalytic asymmetric aziridination reaction is developed to give aziridine-2-carboxylic esters with very high diastereo- and enantioselectivity from aromatic and aliphatic aldehydes. This new method pushes the boundary of the aziridination reaction to substrates that failed with preformed imines.

SUBMITTER: Gupta AK 

PROVIDER: S-EPMC3212731 | biostudies-literature | 2011 Nov

REPOSITORIES: biostudies-literature