1-(2-Hy-droxy-eth-yl)-4-[3-(2-trifluoro-methyl-9H-thioxanthen-9-yl-idene)prop-yl]piperazine-1,4-diium dichloride: the dihydro-chloride salt of flupentixol.

ABSTRACT: In the title compound, C(23)H(27)F(3)N(2)OS(+)·2Cl(-), the piperazinediium ring adopts a chair conformation. The dihedral angle between the two outer aromatic rings of the 9H-thioxanthene unit is 40.35 (18)°. The F atoms in the trifluoro-methyl group are disordered over two sets of sites with occupancies of 0.803 (6) and 0.197 (6). In the crystal, mol-ecules are connected by N-H⋯Cl, O-H⋯Cl C-H⋯O and C-H⋯Cl hydrogen bonds, forming chains propagating along [001]. There are also C-H⋯π inter-actions present in the crystal structure.

SUBMITTER: Siddegowda MS 

PROVIDER: S-EPMC3213522 | biostudies-literature | 2011 Aug

REPOSITORIES: biostudies-literature