Short and efficient synthetic route to methyl α-trioxacarcinoside B and anomerically activated derivatives.

ABSTRACT: A 9-step synthetic route to the complex carbohydrate methyl α-trioxacarcinoside B from 2-acetylfuran is described. Anomerically activated forms, including 1-phenylthio, 1-O-(4'-pentenyl), 1-fluoro, and 1-O-acetyl derivatives are also prepared.

SUBMITTER: Magauer T 

PROVIDER: S-EPMC3216050 | biostudies-literature | 2011 Oct

REPOSITORIES: biostudies-literature