Predictors of mitral annulus early diastolic velocity: impact of long-axis function, ventricular filling pattern, and relaxation.

ABSTRACT:

Aims

Although left ventricular (LV) relaxation is well recognized as a predictor of mitral annulus (MA) early diastolic (E') velocity, its significance relative to other predictors of E' is less well understood.

Methods and results

We assessed 40 healthy volunteers, 43 patients with acutely decompensated chronic systolic heart failure (HF), and 36 patients with hypertrophic obstructive cardiomyopathy (HOCM) using echocardiography and right or left heart catheterization. Data were obtained at baseline. In addition, in healthy volunteers haemodynamics were varied by graded saline infusion and low body negative pressure, while in HF patients it was varied by vasoactive drug treatment. E- and A-wave velocity (E/A) ratio of the mitral valve inflow, systolic MA velocity integral (

SUBMITTER: Popovic ZB 

PROVIDER: S-EPMC3216376 | biostudies-literature | 2011 Nov

REPOSITORIES: biostudies-literature