An atlas of bovine gene expression reveals novel distinctive tissue characteristics and evidence for improving genome annotation.

ABSTRACT:

Background

A comprehensive transcriptome survey, or gene atlas, provides information essential for a complete understanding of the genomic biology of an organism. We present an atlas of RNA abundance for 92 adult, juvenile and fetal cattle tissues and three cattle cell lines.

Results

The Bovine Gene Atlas was generated from 7.2 million unique digital gene expression tag sequences (300.2 million total raw tag sequences), from which 1.59 million unique tag sequences were identified that mapped to the draft bovine genome accounting for 85% of the total raw tag abundance. Filtering these tags yielded 87,764 unique tag sequences that unambiguously mapped to 16,517 annotated protein-coding loci in the draft genome accounting for 45% of the total raw tag abundance. Clustering of ti

SUBMITTER: Harhay GP 

PROVIDER: S-EPMC3218658 | biostudies-literature | 2010

REPOSITORIES: biostudies-literature