Rapid versus standard intravenous rehydration in paediatric gastroenteritis: pragmatic blinded randomised clinical trial.

ABSTRACT:

Objective

To determine if rapid rather than standard intravenous rehydration results in improved hydration and clinical outcomes when administered to children with gastroenteritis.

Design

Single centre, two arm, parallel randomised pragmatic controlled trial. Blocked randomisation stratified by site. Participants, caregivers, outcome assessors, investigators, and statisticians were blinded to the treatment assignment.

Setting

Paediatric emergency department in a tertiary care centre in Toronto, Canada.

Participants

226 children aged 3 months to 11 years; complete follow-up was obtained on 223 (99%). Eligible children were aged over 90 days, had a diagnosis of dehydration secondary to gastroenteritis, had not responded to oral rehydration, and had been prescribe

SUBMITTER: Freedman SB 

PROVIDER: S-EPMC3219422 | biostudies-literature | 2011 Nov

REPOSITORIES: biostudies-literature