Quantitative CT assessment of emphysema and airways in relation to lung cancer risk.

ABSTRACT:

Purpose

To determine whether quantitative computed tomographic (CT) measurements of emphysema and airway dimensions are associated with lung cancer risk in a screening population.

Materials and methods

Institutional review board approval and informed consent for the use of deidentified images were obtained. In this retrospective study, CT scans were analyzed from 279 participants in the CT screening arm of the National Lung Screening Trial who were diagnosed with lung cancer and 279 participants who were not diagnosed with lung cancer after a median follow-up period of 6.6 years. Quantitative CT measurements of emphysema and right upper lobe apical segmental and subsegmental airway dimensions, and multiple patient history-related variables, were compared between the two grou

SUBMITTER: Gierada DS 

PROVIDER: S-EPMC3219910 | biostudies-literature | 2011 Dec

REPOSITORIES: biostudies-literature