A novel mode of chromosomal evolution peculiar to filamentous Ascomycete fungi.

ABSTRACT:

Background

Gene loss, inversions, translocations, and other chromosomal rearrangements vary among species, resulting in different rates of structural genome evolution. Major chromosomal rearrangements are rare in most eukaryotes, giving large regions with the same genes in the same order and orientation across species. These regions of macrosynteny have been very useful for locating homologous genes in different species and to guide the assembly of genome sequences. Previous analyses in the fungi have indicated that macrosynteny is rare; instead, comparisons across species show no synteny or only microsyntenic regions encompassing usually five or fewer genes. To test the hypothesis that chromosomal evolution is different in the fungi compared to other eukaryotes, synteny was compar

SUBMITTER: Hane JK 

PROVIDER: S-EPMC3219968 | biostudies-literature | 2011

REPOSITORIES: biostudies-literature