Temperature dependence of the extrinsic incubation period of orbiviruses in Culicoides biting midges.

ABSTRACT:

Background

The rate at which viruses replicate and disseminate in competent arthropod vectors is limited by the temperature of their environment, and this can be an important determinant of geographical and seasonal limits to their transmission by arthropods in temperate regions.

Methodology/principal findings

Here, we present a novel statistical methodology for estimating the relationship between temperature and the extrinsic incubation period (EIP) and apply it to both published and novel data on virus replication for three internationally important orbiviruses (African horse sickness virus (AHSV), bluetongue virus (BTV) and epizootic haemorrhagic disease virus (EHDV)) in their Culicoides vectors. Our analyses show that there can be differences in vector competence for dif

SUBMITTER: Carpenter S 

PROVIDER: S-EPMC3220716 | biostudies-literature | 2011

REPOSITORIES: biostudies-literature