Acute kidney injury in patients with acute lung injury: impact of fluid accumulation on classification of acute kidney injury and associated outcomes.

ABSTRACT:

Objective

It has been suggested that fluid accumulation may delay recognition of acute kidney injury. We sought to determine the impact of fluid balance on the incidence of nondialysis requiring acute kidney injury in patients with acute lung injury and to describe associated outcomes, including mortality.

Design

Analysis of the Fluid and Catheter Treatment Trial, a factorial randomized clinical trial of conservative vs. liberal fluid management and of management guided by a central venous vs. pulmonary artery catheter.

Setting

Acute Respiratory Distress Syndrome Network hospitals.

Patients

One thousand patients.

Interventions

None.

Measurements and main results

The incidence of acute kidney injury, defined as an absolute rise in creatinine of ≥0.

SUBMITTER: Liu KD 

PROVIDER: S-EPMC3220741 | biostudies-literature | 2011 Dec

REPOSITORIES: biostudies-literature