Genome-wide identification and characterization of ATP-binding cassette transporters in the silkworm, Bombyx mori.

ABSTRACT:

Background

The ATP-binding cassette (ABC) transporter superfamily is the largest transporter gene family responsible for transporting specific molecules across lipid membranes in all living organisms. In insects, ABC transporters not only have important functions in molecule transport, but also play roles in insecticide resistance, metabolism and development.

Results

From the genome of the silkworm, Bombyx mori, we have identified 51 putative ABC genes which are classified into eight subfamilies (A-H) by phylogenetic analysis. Gene duplication is very evident in the ABCC and ABCG subfamilies, whereas gene numbers and structures are well conserved in the ABCD, ABCE, ABCF, and ABCH subfamilies. Microarray analysis revealed that expression of 32 silkworm ABC genes can be detect

SUBMITTER: Liu S 

PROVIDER: S-EPMC3224256 | biostudies-literature | 2011 Oct

REPOSITORIES: biostudies-literature