How yeast re-programmes its transcriptional profile in response to different nutrient impulses.

ABSTRACT:

Background

A microorganism is able to adapt to changes in its physicochemical or nutritional environment and this is crucial for its survival. The yeast, Saccharomyces cerevisiae, has developed mechanisms to respond to such environmental changes in a rapid and effective manner; such responses may demand a widespread re-programming of gene activity. The dynamics of the re-organization of the cellular activities of S. cerevisiae in response to the sudden and transient removal of either carbon or nitrogen limitation has been studied by following both the short- and long-term changes in yeast's transcriptomic profiles.

Results

The study, which spans timescales from seconds to hours, has revealed the hierarchy of metabolic and genetic regulatory switches that allow yeast to adapt

SUBMITTER: Dikicioglu D 

PROVIDER: S-EPMC3224505 | biostudies-literature | 2011 Sep

REPOSITORIES: biostudies-literature