Post-fasting olfactory, transcriptional, and feeding responses in Drosophila.

ABSTRACT: The sensation of hunger after a period of fasting and of satiety after eating is crucial to behavioral regulation of food intake, but the biological mechanisms regulating these sensations are incompletely understood. We studied the behavioral and physiological adaptations to fasting in the vinegar fly (Drosophila melanogaster). Here we show that both male and female flies increased their rate of food intake transiently in the post-fasted state. Although the basal feeding rate was higher in females than males, the magnitude of the post-fasting feeding response was the same in both sexes. Flies returned to a stable baseline feeding rate within 12 h after return to food for males and 24 h for females. This modulation in feeding was accompanied by a significant increase in the size of the crop

SUBMITTER: Farhadian SF 

PROVIDER: S-EPMC3225490 | biostudies-literature | 2012 Jan

REPOSITORIES: biostudies-literature