The Environmental Polymorphism Registry: a unique resource that facilitates translational research of environmental disease.

ABSTRACT:

Background

Dissecting complex disease has become more feasible because of the availability of large-scale DNA resources and advances in high-throughput genomic technology. Although these tools help scientists identify potential susceptibility loci, subjects with relevant genotypes are needed for clinical phenotyping and toxicity studies.

Objective

We have developed a resource of subjects and their DNA to use for translational research of environmental disease.

Methods

More than 15,000 individuals of diverse sex, age, race, and ethnicity were recruited from North Carolina. DNA was isolated from their blood and coded with personal identification numbers linked to their identities. This linked resource of subjects and their DNA-the Environmental Polymorphism Registry (EP

SUBMITTER: Chulada PC 

PROVIDER: S-EPMC3226495 | biostudies-literature | 2011 Nov

REPOSITORIES: biostudies-literature