Ontology highlight
ABSTRACT:
SUBMITTER: Koire AM
PROVIDER: S-EPMC3229123 | biostudies-literature | 2011 Oct
REPOSITORIES: biostudies-literature
Genetics and molecular biology 20111001 4
Gene fusions, yielding the formation of multidomain proteins, are evolutionary events that can be utilized as phylogenetic markers. Here we describe a fusion gene comprising the α and β subunits of succinyl-coA synthetase, an enzyme of the TCA cycle, in Pezizomycotina fungi. This fusion is present in all Pezizomycotina with complete genome sequences and absent from all other organisms. Phylogenetic analysis of the α and β subunits of succinyl-CoA synthetase suggests that both subunits were dupli ...[more]