Imiquimod for the treatment of genital warts: a quantitative systematic review.

ABSTRACT:

Objective

To review published randomised controlled trials to assess the benefit and harm of imiquimod in the treatment of external genital warts.

Data sources

MEDLINE (1966 - December 2000), Cochrane Library (Issue 3, 2000) and PubMed (December 15, 2000), review articles and reference lists.

Review methods

Included studies had to be randomised trials of imiquimod, to be full published papers, and to have a comparison group. Quality of trial reporting was assessed. Relative benefit and number needed to treat were calculated for the main outcomes of wart clearance at the end of therapy, of at least 50% reduction in wart area, and of complete clearance at the end of treatment and no recurrence of warts during a follow-up period, as well as for adverse effect withdrawal

SUBMITTER: Moore RA 

PROVIDER: S-EPMC32301 | biostudies-literature | 2001

REPOSITORIES: biostudies-literature