In-traffic air pollution exposure and CC16, blood coagulation, and inflammation markers in healthy adults.

ABSTRACT:

Background

Exposure to traffic-related air pollution is a risk factor for cardiovascular events, probably involving mechanisms of inflammation and coagulation. Little is known about effects of the short exposures encountered while participating in traffic.

Objectives

The objective of the study was to examine effects of exposure of commuters to air pollution on cardiovascular biomarkers.

Methods

Thirty-four healthy adult volunteers commuted for 2 hr by bus, car, or bicycle during the morning rush hour. During the commute, exposure to particle number, particulate matter (PM) ≤ 2.5 µm in aerodynamic diameter (PM2.5), PM ≤ 10 µm in diameter (PM10), and soot was measured. We estimated inhaled doses based on heart rate monitoring. Shortly before exposure and 6 hr after expo

SUBMITTER: Zuurbier M 

PROVIDER: S-EPMC3230432 | biostudies-literature | 2011 Oct

REPOSITORIES: biostudies-literature