Acute respiratory inflammation in children and black carbon in ambient air before and during the 2008 Beijing Olympics.

ABSTRACT:

Background

Epidemiologic evidence for a causative association between black carbon (BC) and health outcomes is limited.

Objectives

We estimated associations and exposure-response relationships between acute respiratory inflammation in schoolchildren and concentrations of BC and particulate matter with an aerodynamic diameter of ≤ 2.5 μm (PM2.5) in ambient air before and during the air pollution intervention for the 2008 Beijing Olympics.

Methods

We measured exhaled nitric oxide (eNO) as an acute respiratory inflammation biomarker and hourly mean air pollutant concentrations to estimate BC and PM2.5 exposure. We used 1,581 valid observations of 36 subjects over five visits in 2 years to estimate associations of eNO with BC and PM2.5 according to generalized estimating

SUBMITTER: Lin W 

PROVIDER: S-EPMC3230448 | biostudies-literature | 2011 Oct

REPOSITORIES: biostudies-literature