Evolutionary factors affecting Lactate dehydrogenase A and B variation in the Daphnia pulex species complex.

ABSTRACT:

Background

Evidence for historical, demographic and selective factors affecting enzyme evolution can be obtained by examining nucleotide sequence variation in candidate genes such as Lactate dehydrogenase (Ldh). Two closely related Daphnia species can be distinguished by their electrophoretic Ldh genotype and habitat. Daphnia pulex populations are fixed for the S allele and inhabit temporary ponds, while D. pulicaria populations are fixed for the F allele and inhabit large stratified lakes. One locus is detected in most allozyme surveys, but genome sequencing has revealed two genes, LdhA and LdhB.

Results

We sequenced both Ldh genes from 70 isolates of these two species from North America to determine if the association between Ldh genotype and habitat shows evidence for sel

SUBMITTER: Crease TJ 

PROVIDER: S-EPMC3231769 | biostudies-literature | 2011 Jul

REPOSITORIES: biostudies-literature