The muscle pattern of the Drosophila abdomen depends on a subdivision of the anterior compartment of each segment.

ABSTRACT: In the past, segments were defined by landmarks such as muscle attachments, notably by Snodgrass, the king of insect anatomists. Here, we show how an objective definition of a segment, based on developmental compartments, can help explain the dorsal abdomen of adult Drosophila. The anterior (A) compartment of each segment is subdivided into two domains of cells, each responding differently to Hedgehog. The anterior of these domains is non-neurogenic and clones lacking Notch develop normally; this domain can express stripe and form muscle attachments. The posterior domain is neurogenic and clones lacking Notch do not form cuticle; this domain is unable to express stripe or form muscle attachments. The posterior (P) compartment does not form muscle attachments. Our in vivo films indicate tha

SUBMITTER: Krzemien J 

PROVIDER: S-EPMC3231773 | biostudies-literature | 2012 Jan

REPOSITORIES: biostudies-literature