Genetic analysis and morphological identification of pilus-like structures in members of the genus Bifidobacterium.

ABSTRACT:

Background

Cell surface pili in Gram positive bacteria have been reported to orchestrate the colonization of host tissues, evasion of immunity and the development of biofilms. So far, little if any information is available on the presence of pilus-like structures in human gut commensals like bifidobacteria.

Results and discussion

In this report, Atomic Force Microscopy (AFM) of various bifidobacterial strains belonging to Bifidobacterium bifidum, Bifidobacterium longum subsp. longum, Bifidobacterium dentium, Bifidobacterium adolescentis and Bifidobacterium animalis subsp. lactis revealed the existence of appendages resembling pilus-like structures. Interestingly, these microorganisms harbour two to six predicted pilus gene clusters in their genome, with each organized in an

SUBMITTER: Foroni E 

PROVIDER: S-EPMC3231923 | biostudies-literature | 2011 Aug

REPOSITORIES: biostudies-literature