An automatic method for CASP9 free modeling structure prediction assessment.

ABSTRACT:

Motivation

Manual inspection has been applied to and is well accepted for assessing critical assessment of protein structure prediction (CASP) free modeling (FM) category predictions over the years. Such manual assessment requires expertise and significant time investment, yet has the problems of being subjective and unable to differentiate models of similar quality. It is beneficial to incorporate the ideas behind manual inspection to an automatic score system, which could provide objective and reproducible assessment of structure models.

Results

Inspired by our experience in CASP9 FM category assessment, we developed an automatic superimposition independent method named Quality Control Score (QCS) for structure prediction assessment. QCS captures both global and local stru

SUBMITTER: Cong Q 

PROVIDER: S-EPMC3232368 | biostudies-literature | 2011 Dec

REPOSITORIES: biostudies-literature