Hypercalciuria associated with high dietary protein intake is not due to acid load.

ABSTRACT:

Context and objective

Dietary intake of animal proteins is associated with an increase in urinary calcium and nephrolithiasis risk. We tested the hypothesis that the acid load imposed by dietary proteins causes this hypercalciuria.

Design and setting

In a short-term crossover metabolic study, an alkali salt was provided with a high-protein diet (HPD) to neutralize the acid load imparted by dietary proteins.

Participants and interventions

Eleven healthy volunteers were evaluated at the end of each of four phases while consuming metabolic diets with fixed calcium and sodium content. Phases 1 and 3 consisted of a control diet (CD). Phases 2 and 4 consisted of a eucaloric HPD (60 g/d animal proteins added to CD). Along with HPD in phases 2 and 4, subjects ingested 30 mEq

SUBMITTER: Maalouf NM 

PROVIDER: S-EPMC3232614 | biostudies-literature | 2011 Dec

REPOSITORIES: biostudies-literature