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Detection of an unusual van genotype in a vancomycin-resistant Enterococcus faecium hospital isolate.


ABSTRACT: We highlight the detection of a rare vanM genotype in Enterococcus faecium. This isolate exhibited a VanB phenotype, with high levels of resistance to vancomycin (MIC, >256 mg/liter) and susceptibility to teicoplanin (MIC, 1 mg/liter). It was, however, vanB negative by PCR. Further screening for other van loci revealed the presence of a complete vanM operon.

SUBMITTER: Teo JW 

PROVIDER: S-EPMC3232975 | biostudies-literature | 2011 Dec

REPOSITORIES: biostudies-literature

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Detection of an unusual van genotype in a vancomycin-resistant Enterococcus faecium hospital isolate.

Teo Jeanette W P JW   Krishnan Prabha P   Jureen Roland R   Lin Raymond T P RT  

Journal of clinical microbiology 20111012 12


We highlight the detection of a rare vanM genotype in Enterococcus faecium. This isolate exhibited a VanB phenotype, with high levels of resistance to vancomycin (MIC, >256 mg/liter) and susceptibility to teicoplanin (MIC, 1 mg/liter). It was, however, vanB negative by PCR. Further screening for other van loci revealed the presence of a complete vanM operon. ...[more]

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