Bidirectional association between depression and obesity in middle-aged and older women.

ABSTRACT:

Objective

Although it has been hypothesized that the depression-obesity relation is bidirectional, few studies have addressed this hypothesis in a prospective setting. We aimed to examine the bidirectional relationship in middle-aged and elderly women.

Subjects

A total of 65 955 women aged 54-79 years in the Nurses' Health Study were prospectively followed from 1996 to 2006 with updated information on body weight, depression status and various covariates every 2 years. Depression was defined as self-report of physician-diagnosed depression and/or antidepressant use. Obesity was defined as a BMI ≥30.0 kg m(-2). The first three waves (1996-2000) were used as the baseline period and the last three waves (2002-2006) were used as the follow-up period.

Results

After adjusti

SUBMITTER: Pan A 

PROVIDER: S-EPMC3233636 | biostudies-literature | 2012 Apr

REPOSITORIES: biostudies-literature