Seroepidemiology and molecular characterization of hepatitis E Virus in Macaca mulatta from a village in Yunnan, China, where infection with this virus is endemic.

ABSTRACT:

Background

Hepatitis E virus (HEV) infection is a significant public health concern and has been identified as a zoonotic infection.

Objectives

Since no reports have characterized the epidemiological and genotypic features of HEV infections in Macaca mulatta (rhesus macaques) from Yunnan, China, where swine HEV infections are endemic, we aimed to investigate these characteristics.

Materials and methods

Seroepidemiological and molecular characterization of HEV in both Macaca mulatta and pigs from the Yunnan province of China were conducted using enzyme-linked immunosorbent assay (ELISA) and reverse transcription-nested PCR (RT-nPCR). Four hundred and eighty-two stool samples (320 from Macaca mulatta and 162 from pigs) and 92 serum samples (all from Macaca mulatta) were

SUBMITTER: Huang F 

PROVIDER: S-EPMC3234536 | biostudies-literature | 2011 Sep

REPOSITORIES: biostudies-literature