Enantioselective and regioselective indium(III)-catalyzed addition of pyrroles to isatins.

ABSTRACT: The indium(III)-catalyzed enantioselective and regioselective addition of pyrroles to isatins is described. The effects of metal and solvent on the reactivity and selectivity are compared and discussed, demonstrating that the indium(III)-indapybox complex provides the most effective catalyst. A case of divergent reactivity between pyrroles and indoles is presented.

SUBMITTER: Gutierrez EG 

PROVIDER: S-EPMC3235954 | biostudies-literature | 2011 Nov

REPOSITORIES: biostudies-literature