Solving the Problem: Genome Annotation Standards before the Data Deluge.

ABSTRACT: The promise of genome sequencing was that the vast undiscovered country would be mapped out by comparison of the multitude of sequences available and would aid researchers in deciphering the role of each gene in every organism. Researchers recognize that there is a need for high quality data. However, different annotation procedures, numerous databases, and a diminishing percentage of experimentally determined gene functions have resulted in a spectrum of annotation quality. NCBI in collaboration with sequencing centers, archival databases, and researchers, has developed the first international annotation standards, a fundamental step in ensuring that high quality complete prokaryotic genomes are available as gold standard references. Highlights include the development of annotation assess

SUBMITTER: Klimke W 

PROVIDER: S-EPMC3236044 | biostudies-literature | 2011 Oct

REPOSITORIES: biostudies-literature