Plantagora: modeling whole genome sequencing and assembly of plant genomes.

ABSTRACT:

Background

Genomics studies are being revolutionized by the next generation sequencing technologies, which have made whole genome sequencing much more accessible to the average researcher. Whole genome sequencing with the new technologies is a developing art that, despite the large volumes of data that can be produced, may still fail to provide a clear and thorough map of a genome. The Plantagora project was conceived to address specifically the gap between having the technical tools for genome sequencing and knowing precisely the best way to use them.

Methodology/principal findings

For Plantagora, a platform was created for generating simulated reads from several different plant genomes of different sizes. The resulting read files mimicked either 454 or Illumina reads, with

SUBMITTER: Barthelson R 

PROVIDER: S-EPMC3236183 | biostudies-literature | 2011

REPOSITORIES: biostudies-literature