HOMER: a human organ-specific molecular electronic repository.

ABSTRACT:

Background

Each organ has a specific function in the body. "Organ-specificity" refers to differential expressions of the same gene across different organs. An organ-specific gene/protein is defined as a gene/protein whose expression is significantly elevated in a specific human organ. An "organ-specific marker" is defined as an organ-specific gene/protein that is also implicated in human diseases related to the organ. Previous studies have shown that identifying specificity for the organ in which a gene or protein is significantly differentially expressed, can lead to discovery of its function. Most currently available resources for organ-specific genes/proteins either allow users to access tissue-specific expression over a limited range of organs, or do not contain disease informa

SUBMITTER: Zhang F 

PROVIDER: S-EPMC3236847 | biostudies-literature | 2011 Oct

REPOSITORIES: biostudies-literature