Depression and risk of stroke morbidity and mortality: a meta-analysis and systematic review.

ABSTRACT:

Context

Several studies have suggested that depression is associated with an increased risk of stroke; however, the results are inconsistent.

Objective

To conduct a systematic review and meta-analysis of prospective studies assessing the association between depression and risk of developing stroke in adults.

Data sources

A search of MEDLINE, EMBASE, and PsycINFO databases (to May 2011) was supplemented by manual searches of bibliographies of key retrieved articles and relevant reviews.

Study selection

We included prospective cohort studies that reported risk estimates of stroke morbidity or mortality by baseline or updated depression status assessed by self-reported scales or clinician diagnosis.

Data extraction

Two independent reviewers extracted data o

SUBMITTER: Pan A 

PROVIDER: S-EPMC3242806 | biostudies-literature | 2011 Sep

REPOSITORIES: biostudies-literature