The toxic effects of cigarette additives. Philip Morris' project mix reconsidered: an analysis of documents released through litigation.

ABSTRACT:

Background

In 2009, the promulgation of US Food and Drug Administration (FDA) tobacco regulation focused attention on cigarette flavor additives. The tobacco industry had prepared for this eventuality by initiating a research program focusing on additive toxicity. The objective of this study was to analyze Philip Morris' Project MIX as a case study of tobacco industry scientific research being positioned strategically to prevent anticipated tobacco control regulations.

Methods and findings

We analyzed previously secret tobacco industry documents to identify internal strategies for research on cigarette additives and reanalyzed tobacco industry peer-reviewed published results of this research. We focused on the key group of studies conducted by Phillip Morris in a coordinated

SUBMITTER: Wertz MS 

PROVIDER: S-EPMC3243707 | biostudies-literature | 2011 Dec

REPOSITORIES: biostudies-literature