A deep insight into the sialotranscriptome of the gulf coast tick, Amblyomma maculatum.

ABSTRACT:

Background

Saliva of blood sucking arthropods contains compounds that antagonize their hosts' hemostasis, which include platelet aggregation, vasoconstriction and blood clotting; saliva of these organisms also has anti-inflammatory and immunomodullatory properties. Perhaps because hosts mount an active immune response against these compounds, the diversity of these compounds is large even among related blood sucking species. Because of these properties, saliva helps blood feeding as well as help the establishment of pathogens that can be transmitted during blood feeding.

Methodology/principal findings

We have obtained 1,626,969 reads by pyrosequencing a salivary gland cDNA library from adult females Amblyomma maculatum ticks at different times of feeding. Assembly of this da

SUBMITTER: Karim S 

PROVIDER: S-EPMC3244413 | biostudies-literature | 2011

REPOSITORIES: biostudies-literature