Influenza vaccination for immunocompromised patients: systematic review and meta-analysis from a public health policy perspective.

ABSTRACT:

Background

Immunocompromised patients are vulnerable to severe or complicated influenza infection. Vaccination is widely recommended for this group. This systematic review and meta-analysis assesses influenza vaccination for immunocompromised patients in terms of preventing influenza-like illness and laboratory confirmed influenza, serological response and adverse events.

Methodology/principal findings

Electronic databases and grey literature were searched and records were screened against eligibility criteria. Data extraction and risk of bias assessments were performed in duplicate. Results were synthesised narratively and meta-analyses were conducted where feasible. Heterogeneity was assessed using I(2) and publication bias was assessed using Begg's funnel plot and Egger's

SUBMITTER: Beck CR 

PROVIDER: S-EPMC3245259 | biostudies-literature | 2011

REPOSITORIES: biostudies-literature