Bidirectional plasticity of cortical pattern recognition and behavioral sensory acuity.

ABSTRACT: Learning to adapt to a complex and fluctuating environment requires the ability to adjust neural representations of sensory stimuli. Through pattern completion processes, cortical networks can reconstruct familiar patterns from degraded input patterns, whereas pattern separation processes allow discrimination of even highly overlapping inputs. Here we show that the balance between pattern separation and completion is experience dependent. Rats given extensive training with overlapping complex odorant mixtures showed improved behavioral discrimination ability and enhanced piriform cortical ensemble pattern separation. In contrast, behavioral training to disregard normally detectable differences between overlapping mixtures resulted in impaired piriform cortical ensemble pattern separation (

SUBMITTER: Chapuis J 

PROVIDER: S-EPMC3245808 | biostudies-literature | 2011 Nov

REPOSITORIES: biostudies-literature