Cognitive function and dialysis adequacy: no clear relationship.

ABSTRACT:

Background/aims

Cognitive impairment is common in hemodialysis patients and may be impacted by multiple patient and treatment characteristics. The impact of dialysis dose on cognitive function remains uncertain, particularly in the current era of increased dialysis dose and flux.

Methods

We explored the cross-sectional relationship between dialysis adequacy and cognitive function in a cohort of maintenance hemodialysis patients. Adequacy was defined as the average of the 3 most proximate single pool Kt/V assessments. A detailed neurocognitive battery was administered during the 1st hour of dialysis. Multivariable linear regression models were adjusted for age, sex, education, race and other clinical and demographic characteristics.

Results

Among 273 patients who under

SUBMITTER: Giang LM 

PROVIDER: S-EPMC3245831 | biostudies-literature | 2011

REPOSITORIES: biostudies-literature