Mitigating cellular inflammation in older adults: a randomized controlled trial of Tai Chi Chih.

ABSTRACT:

Objectives

To evaluate the effects of a behavioral intervention, Tai Chi Chih (TCC) on circulating markers of inflammation in older adults.

Design

A prospective, randomized, controlled trial with allocation to two arms, TCC and health education (HE), 16 weeks of intervention administration, and 9 weeks follow-up.

Participants

A total of 83 healthy older adults, aged 59 to 86 years.

Measurements

The primary endpoint was circulating levels of interleukin 6 (IL-6). Secondary outcomes were circulating levels of C-reactive protein, soluble IL-1 receptor antagonist, soluble IL-6 receptor, soluble intercellular adhesion molecule, and IL-18. Severity of depressive symptoms, sleep quality, and physical activity was also assessed over the treatment trial.

Results

SUBMITTER: Irwin MR 

PROVIDER: S-EPMC3247625 | biostudies-literature | 2012 Sep

REPOSITORIES: biostudies-literature