Whole mitochondrial genome sequencing of domestic horses reveals incorporation of extensive wild horse diversity during domestication.

ABSTRACT:

Background

DNA target enrichment by micro-array capture combined with high throughput sequencing technologies provides the possibility to obtain large amounts of sequence data (e.g. whole mitochondrial DNA genomes) from multiple individuals at relatively low costs. Previously, whole mitochondrial genome data for domestic horses (Equus caballus) were limited to only a few specimens and only short parts of the mtDNA genome (especially the hypervariable region) were investigated for larger sample sets.

Results

In this study we investigated whole mitochondrial genomes of 59 domestic horses from 44 breeds and a single Przewalski horse (Equus przewalski) using a recently described multiplex micro-array capture approach. We found 473 variable positions within the domestic horses, 2

SUBMITTER: Lippold S 

PROVIDER: S-EPMC3247663 | biostudies-literature | 2011 Nov

REPOSITORIES: biostudies-literature