CT angiography source images acquired with a fast-acquisition protocol overestimate infarct core on diffusion weighted images in acute ischemic stroke.

ABSTRACT:

Background and purpose

Studies have demonstrated that computed tomography (CT) angiography source images (CTA-SI) acquired under near-steady-state contrast concentration provide infarct core estimates equivalent to diffusion-weighted images (DWI). We sought to test this relationship using our current CTA protocol optimized for faster scan acquisition.

Methods

Forty-eight consecutive acute ischemic stroke patients met the following criteria: fast-acquisition CTA and magnetic resonance imaging (MRI) within 9 hours of symptom onset, CTA-to-MRI interval under 2 hours, and anterior circulation vessel occlusion. Collaterals were graded on CTA, and lesion volumes were calculated on CTA-SI, DWI, and MR mean transit time (MTT) maps.

Results

The mean CTA-to-MRI interval was 36

SUBMITTER: Yoo AJ 

PROVIDER: S-EPMC3248622 | biostudies-literature | 2012 Oct

REPOSITORIES: biostudies-literature