Linking empirical estimates of body burden of environmental chemicals and wellness using NHANES data.

ABSTRACT: Biomonitoring of industrial chemicals in human tissues and fluids has shown that all people carry a "body burden" of synthetic chemicals. Although measurement of an environmental chemical in a person's tissues/fluids is an indication of exposure, it does not necessarily mean the exposure concentration is sufficient to cause an adverse effect. Since humans are exposed to multiple chemicals, there may be a combination effect (e.g., additive, synergistic) associated with low-level exposures to multiple classes of contaminants, which may impact a variety of organ systems. The objective of this research is to link measures of body burden of environmental chemicals and a "holistic" measure of wellness. The approach is demonstrated using biomonitoring data from the National Health and Nutrition E

SUBMITTER: Gennings C 

PROVIDER: S-EPMC3249606 | biostudies-literature | 2012 Feb

REPOSITORIES: biostudies-literature