Ontology highlight
ABSTRACT:
SUBMITTER: van Meeteren LA
PROVIDER: S-EPMC3250609 | biostudies-literature | 2012 Jan
REPOSITORIES: biostudies-literature
van Meeteren Laurens A LA ten Dijke Peter P
Cell and tissue research 20110825 1
Recent evidence has demonstrated that endothelial cells can have a remarkable plasticity. By a process called Endothelial-to-Mesenchymal Transition (EndMT) endothelial cells convert to a more mesenchymal cell type that can give rise to cells such as fibroblasts, but also bone cells. EndMT is essential during embryonic development and tissue regeneration. Interestingly, it also plays a role in pathological conditions like fibrosis of organs such as the heart and kidney. In addition, EndMT contrib ...[more]