Biomarker-calibrated dietary energy and protein intake associations with diabetes risk among postmenopausal women from the Women's Health Initiative.

ABSTRACT:

Background

Self-report of dietary energy and protein intakes has been shown to be systematically and differentially underreported.

Objective

We assessed and compared the association of diabetes among postmenopausal women with biomarker-calibrated and uncalibrated dietary energy and protein intakes from food-frequency questionnaires (FFQs).

Design

The analyses were performed for 74,155 participants of various race-ethnicities from the Women's Health Initiative. Uncalibrated and calibrated energy and protein intakes from FFQs were assessed for associations with incident diabetes by using HR estimates based on Cox regression.

Results

A 20% increment in uncalibrated energy consumption was associated with increased diabetes risk (HR) of 1.03 (95% CI: 1.01, 1.05), 2.

SUBMITTER: Tinker LF 

PROVIDER: S-EPMC3252553 | biostudies-literature | 2011 Dec

REPOSITORIES: biostudies-literature