Increased variability of motor cortical excitability to transcranial magnetic stimulation in migraine: a new clue to an old enigma.

ABSTRACT: Increased, decreased or normal excitability to transcranial magnetic stimulation (TMS) has been reported in the motor (M1) and visual cortices of patients with migraine. Light deprivation (LD) has been reported to modulate M1 excitability in control subjects (CS). Still, effects of LD on M1 excitability compared to exposure to environmental light exposure (EL) had not been previously described in patients with migraine (MP). To further our knowledge about differences between CS and MP, regarding M1 excitability and effects of LD on M1 excitability, we opted for a novel approach by extending measurement conditions. We measured motor thresholds (MTs) to TMS, short-interval intracortical inhibition, and ratios between motor-evoked potential amplitudes and supramaximal M responses in MP and CS

SUBMITTER: Conforto AB 

PROVIDER: S-EPMC3253159 | biostudies-literature | 2012 Jan

REPOSITORIES: biostudies-literature