Source cancellation profiles of electroencephalography and magnetoencephalography.

ABSTRACT: Recorded electric potentials and magnetic fields due to cortical electrical activity have spatial spread even if their underlying brain sources are focal. Consequently, as a result of source cancellation, loss in signal amplitude and reduction in the effective signal-to-noise ratio can be expected when distributed sources are active simultaneously. Here we investigate the cancellation effects of EEG and MEG through the use of an anatomically correct forward model based on structural MRI acquired from 7 healthy adults. A boundary element model (BEM) with four compartments (brain, cerebrospinal fluid, skull and scalp) and highly accurate cortical meshes (~300,000 vertices) were generated. Distributed source activations were simulated using contiguous patches of active dipoles. To investigate

SUBMITTER: Irimia A 

PROVIDER: S-EPMC3254784 | biostudies-literature | 2012 Feb

REPOSITORIES: biostudies-literature