α1,3 glucans are dispensable in Aspergillus fumigatus.

ABSTRACT: A triple α1,3 glucan synthase mutant of Aspergillus fumigatus obtained by successive deletions of the three α1,3 glucan synthase genes (AGS1, AGS2, and AGS3) has a cell wall devoid of α1,3 glucans. The lack of α1,3 glucans affects neither conidial germination nor mycelial vegetative growth and is compensated by an increase in β1,3 glucan and/or chitin content.

SUBMITTER: Henry C 

PROVIDER: S-EPMC3255942 | biostudies-literature | 2012 Jan

REPOSITORIES: biostudies-literature