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Identification and analysis of a glutamatergic local interneuron lineage in the adult Drosophila olfactory system.


ABSTRACT:

Background

The antennal lobe of Drosophila is perhaps one of the best understood neural circuits, because of its well-described anatomical and functional organization and ease of genetic manipulation. Olfactory lobe interneurons - key elements of information processing in this network - are thought to be generated by three identified central brain neuroblasts, all of which generate projection neurons. One of these neuroblasts, located lateral to the antennal lobe, also gives rise to a population of local interneurons, which can either be inhibitory (GABAergic) or excitatory (cholinergic). Recent studies of local interneuron number and diversity suggest that additional populations of this class of neurons exist in the antennal lobe. This implies that other, as yet unidentified, neur

SUBMITTER: Das A 

PROVIDER: S-EPMC3257541 | biostudies-literature | 2011 Jan

REPOSITORIES: biostudies-literature