Body composition and coronary heart disease mortality--an obesity or a lean paradox?

ABSTRACT:

Objective

To determine the combined effects of body mass index (BMI) and body fat (BF) on prognosis in coronary heart disease (CHD) to better understand the obesity paradox.

Patients and methods

We studied 581 patients with CHD between January 1, 2000, and July 31, 2005, who were divided into low (<25) and high BMI (≥25), as well as low (≤25% men and ≤35% women) and high BF (>25% in men and >35% in women). Four groups were analyzed by total mortality during the 3-year follow-up by National Death Index: low BF/low BMI (n=119), high BF/low BMI (n=26), low BF/high BMI (n=125), and high BF/high BMI (n=311).

Results

During the 3-year follow-up, mortality was highest in the low BF/low BMI group (11%), which was significantly (P<.001) higher than that in the other 3 groups (

SUBMITTER: Lavie CJ 

PROVIDER: S-EPMC3257992 | biostudies-literature | 2011 Sep

REPOSITORIES: biostudies-literature