Flavonoid intake and cardiovascular disease mortality in a prospective cohort of US adults.

ABSTRACT:

Background

Flavonoids are plant-based phytochemicals with cardiovascular protective properties. Few studies have comprehensively examined flavonoid classes in relation to cardiovascular disease mortality.

Objective

We examined the association between flavonoid intake and cardiovascular disease (CVD) mortality among participants in a large, prospective US cohort.

Design

In 1999, a total of 38,180 men and 60,289 women in the Cancer Prevention Study II Nutrition Cohort with a mean age of 70 and 69 y, respectively, completed questionnaires on medical history and lifestyle behaviors, including a 152-item food-frequency questionnaire. Cox proportional hazards modeling was used to calculate multivariate-adjusted hazard RRs and 95% CIs for associations between total flavonoid

SUBMITTER: McCullough ML 

PROVIDER: S-EPMC3260072 | biostudies-literature | 2012 Feb

REPOSITORIES: biostudies-literature