Detection and quantification of poliovirus infection using FTIR spectroscopy and cell culture.

ABSTRACT:

Background

In a globalized word, prevention of infectious diseases is a major challenge. Rapid detection of viable virus particles in water and other environmental samples is essential to public health risk assessment, homeland security and environmental protection. Current virus detection methods, especially assessing viral infectivity, are complex and time-consuming, making point-of-care detection a challenge. Faster, more sensitive, highly specific methods are needed to quantify potentially hazardous viral pathogens and to determine if suspected materials contain viable viral particles. Fourier transform infrared (FTIR) spectroscopy combined with cellular-based sensing, may offer a precise way to detect specific viruses. This approach utilizes infrared light to monitor changes i

SUBMITTER: Lee-Montiel FT 

PROVIDER: S-EPMC3260089 | biostudies-literature | 2011 Dec

REPOSITORIES: biostudies-literature